pentobarbital will reduce the extent or effect of ritonavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital will decrease the level or result of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Powerful CYP3A4 inducers may possibly lessen midostaurin con